BIRTH OF PROJECTION NEURONS IN ADULT AVIAN BRAIN MAY BE RELATED TO PERCEPTUAL OR MOTOR LEARNING
BIRTH OF PROJECTION NEURONS IN ADULT AVIAN BRAIN MAY BE RELATED TO PERCEPTUAL OR MOTOR LEARNING
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DOI：
10.1126/science.1698312
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发表时间：
1990-09-21
期刊：
影响因子：
56.9
通讯作者：
NOTTEBOHM, F
中科院分区：
文献类型：
--
作者：
ALVAREZBUYLLA, A;KIRN, JR;NOTTEBOHM, F
在成年金丝雀和斑胸草雀中，构成控制鸣唱的运动通路一部分的投射神经元继续产生，并取代较老的投射神经元。这是通过结合[3H]胸苷（一种细胞出生标记物）和荧光金（一种神经元连接的逆行转运示踪剂）来显示的。物种和季节的比较表明，这一过程与获得知觉或运动记忆有关。成年人大脑产生和替换投射神经元的能力应该会影响我们对大脑修复的思考。
Projection neurons that form part of the motor pathway for song control continue to be produced and to replace older projection neurons in adult canaries and zebra finches. This is shown by combining [3H]thymidine, a cell birth marker, and fluorogold, a retrogradely transported tracer of neuronal connectivity. Species and seasonal comparisons suggest that this process is related to the acquisition of perceptual or motor memories. The ability of an adult brain to produce and replace projection neurons should influence our thinking on brain repair.