Assessment of coronary intima-media thickness by optical coherence tomography - Comparison with intravascular ultrasound
Assessment of coronary intima-media thickness by optical coherence tomography - Comparison with intravascular ultrasound
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DOI：
10.1253/circj.69.903
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发表时间：
2005-08-01
影响因子：
3.3
通讯作者：
Yoshida, K
中科院分区：
文献类型：
--
作者：
Kume, T;Akasaka, T;Yoshida, K
背景光学相干层析成像（OCT）是一种新的成像方法。分辨率约为10-20 μ m，比血管内超声（IVUS）高约10倍。方法与结果本研究将冠状动脉内膜-中膜厚度（IMT）及54个冠状动脉段的组织学检查结果与OCT和IVUS结果进行比较。OCT与组织学检查的IMT一致性优于IVUS与组织学检查（r=0.95, p < 0.001， OCT平均差值=-0.01 +/- 0.07mm; r=0.88, p < 0.001， IVUS平均差值=-0.03 +/- 0.10mm）。OCT与组织学检查的内膜厚度吻合较好（r=0.98, p < 0.001，平均差=0.01±0.04mm）。结论OCT能较IVUS更准确地测量IMT。此外，OCT可以评估内膜厚度，并与组织学检查具有良好的相关性。
Background Optical coherence tomography (OCT) is a new imaging method. With a resolution of approximately 10-20 mu m, which is approximately 10-fold higher than that of intravascular ultrasound (IVUS).Methods and Results This study compared the coronary intima-media thickness (IMT) and the intimal thickness of 54 coronary arterial segments evaluated by histological examination with the results of OCT and IVUS. There was better agreement in IMT between OCT and histological examination than between IVUS and histological examination (r=0.95, p < 0.001, mean difference =-0.01 +/- 0.07mm for OCT; r=0.88, p < 0.001, mean difference=-0.03 +/- 0.10mm for IVUS). There was good agreement in the intimal thickness between OCT and histological examination (r=0.98, p < 0.001, mean difference =0.01 +/- 0.04mm).Conclusions IMT could be measured more accurately by OCT than IVUS. In addition, the intimal thickness could be evaluated by OCT and correlated well with the histological examination.