A ROLE FOR FATTY-ACIDS AND LIVER FATTY-ACID BINDING-PROTEIN IN PEROXISOME PROLIFERATION
A ROLE FOR FATTY-ACIDS AND LIVER FATTY-ACID BINDING-PROTEIN IN PEROXISOME PROLIFERATION
复制标题
DOI：
10.1042/bst0200824
复制
发表时间：
1992-11-01
影响因子：
3.9
通讯作者：
GREEN, S
中科院分区：
文献类型：
--
作者：
ISSEMANN, I;PRINCE, R;GREEN, S
I’eroxime 增殖剂是一组不同的化学物质，当给予大鼠和小鼠时会产生肝脏增生和肥大，后者主要是由于肝过氧化物酶体的大小和数量增加所致 [l]。对这些化学物质的兴趣源于它们是啮齿动物肝脏致癌物的观察结果。在标准杆
I’eroxisome proliferators are a diverse group of chemicals which when administered to rats and mice produce liver hyperplasia and hypertrophy, the latter being predominantly due to an increase in the size and number of hepatic peroxisomes [l]. Interest in these chemicals stems from the observation that they are rodent liver carcinogens. In par-