Techniques of assessing muscle mass and function (sarcopenia) for epidemiological studies of the elderly.
Techniques of assessing muscle mass and function (sarcopenia) for epidemiological studies of the elderly.
复制标题
用于老年人流行病学研究的肌肉质量和功能（肌肉减少症）评估技术。
DOI：
10.1093/gerona/50a.special_issue.45
复制
发表时间：
1995
期刊：
影响因子：
--
通讯作者：
Guigoz,Y
中科院分区：
文献类型：
--
作者：
Chumlea,WC;Guo,SS;Vellas,B;Guigoz,Y
对于流行病学研究，需要可靠和有效的肌肉质量测量或指数来筛查有肌肉减少症风险的老年人，并确定这些疾病在全国范围内的流行程度。更适合野外或流行病学背景的方法是人体测量法、生物电阻抗法和握力法。这些实地方法虽然可靠，但在老年人中应用的有效性有限，并且受到老年人有限的功能能力的限制，这些功能能力随着年龄的增长而下降。老年人的流行病学研究需要包括足够数量的不同种族背景和年龄较大的人。对于当今老年人的流行病学研究，还需要选择纳入此类研究的老年人类别：健康、生病、高龄、残疾、功能状态水平等，因为变量之间的关系可能具有不同的统计和生物学关联。今后的工作应着眼于改进流行病学和系列研究的设计和方法，以便最大限度地增加可以研究的老年人的数量和类别。
For epidemiological studies, reliable and valid measurements or indices of muscle mass are needed to screen for those elderly persons at risk for sarcopenia, and to determine the prevalence of these conditions on a national level. The methods more suitable for field or epidemiological settings are anthropometry, bioelectrical impedance, and grip strength. These field methods, while reliable, have limited demonstrated validity in their application to the elderly and are restricted by the limited functional capabilities of the elderly, which decrease with age. Epidemiological studies of the elderly need to include sufficient numbers of persons of different ethnic backgrounds, and at the older ages. For an epidemiological study of the elderly today, one also needs to select the categories of elderly persons to be included in such studies: healthy, sick, very old, handicapped, level of functional status, etc., because relationships among variables can have different statistical and biological associations. Future work should be directed at improving the design and methodology of epidemiological and serial studies so as to maximize the numbers and categories of elderly persons who can be studied.