Gestational trophoblastic disease epidemiology and trends

Gestational trophoblastic disease epidemiology and trends
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DOI:
10.1097/00003081-200309000-00006
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发表时间:
2003-09-01
影响因子:
1.5
通讯作者:
Smith, HO
Smith, HO
中科院分区:
医学4区
文献类型:
--
作者:
Smith, HO

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妊娠滋养细胞疾病 (GTD) 包括一系列相互关联的胎盘滋养细胞病变,其自发消退、局部侵袭和转移的倾向各不相同。所有 GTD 变异都是在先前怀孕后出现的,通常但并非总是与时间相关。 1 尽管有至少 50 年的广泛流行病学数据,但遗传和环境因素(包括种族、年龄和地理位置)对全球 GTD 发病率报告差异的影响程度尚不确定。 2 虽然有多种因素造成,但报告的发病率的许多差异可以通过以下观察来解释:
Gestational trophoblastic disease (GTD) comprises a spectrum of interrelated placental trophoblastic lesions that vary in predilection for spontaneous resolution, local invasion, and metastasis. All GTD variants arise following an antecedent pregnancy, usually, but not always, the one temporally related. 1 Despite extensive epidemiological data spanning at least 50 years, the extent to which genetic and environmental factors including race, age, and geographic location influence the variably in reported differences in incidence rates for GTD throughout the world is uncertain. 2 While multiple factors contribute, many of the differences in reported incidence rates can be accounted for by the following observations: