Nutritional regulation of division of labor in honey bees: toward a systems biology perspective
Nutritional regulation of division of labor in honey bees: toward a systems biology perspective
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DOI：
10.1002/wsbm.73
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发表时间：
2010-09-01
影响因子：
7.9
通讯作者：
Robinson, Gene E.
中科院分区：
文献类型：
--
作者：
Ament, Seth A.;Wang, Ying;Robinson, Gene E.
生物通过表型可塑性过程使其行为和生理适应环境条件。在一个经过充分研究的例子中，工蜂之间的劳动分工涉及到一种定型的但可塑的行为和生理成熟模式。在生命的早期，工蜂负责照顾幼蜂和其他蜂巢内的任务，并拥有大量的内部营养储备;在生命的后期，它们在蜂巢外觅食花蜜和花粉，并拥有少量的营养储备。成熟的速度取决于殖民地的条件，环境，生理和基因组机制，这发生正在积极研究。在这里，我们回顾目前的知识机制，其中一个关键的环境变量，营养状况，影响工人蜜蜂分工。这些研究表明，个体营养状况的变化和保守的食物相关的分子和激素途径调节个体蜜蜂开始觅食的年龄。然后，我们概述了系统生物学方法的方式，通过蜜蜂基因组的测序，将使研究人员能够更深入地了解蜜蜂行为的营养调控，以及一般的表型可塑性。(C)John Wiley & Sons，Inc. WIRES系统生物医学2010 2 566-576
Organisms adapt their behavior and physiology to environmental conditions through processes of phenotypic plasticity. In one well-studied example, the division of labor among worker honey bees involves a stereotyped yet plastic pattern of behavioral and physiological maturation. Early in life, workers perform brood care and other in-hive tasks and have large internal nutrient stores; later in life, they forage for nectar and pollen outside the hive and have small nutrient stores. The pace of maturation depends on colony conditions, and the environmental, physiological, and genomic mechanisms by which this occurs are being actively investigated. Here we review current knowledge of the mechanisms by which a key environmental variable, nutritional status, influences worker honey bee division of labor. These studies demonstrate that changes in individual nutritional status and conserved food-related molecular and hormonal pathways regulate the age at which individual bees begin to forage. We then outline ways in which systems biology approaches, enabled by the sequencing of the honey bee genome, will allow researchers to gain deeper insight into nutritional regulation of honey bee behavior, and phenotypic plasticity in general. (C) 2010 John Wiley & Sons, Inc. WIREs Syst Biol Med 2010 2 566-576