Improvement in various estimates of quality of life after coronary artery bypass grafting in patients with and without a history of hypertension
Improvement in various estimates of quality of life after coronary artery bypass grafting in patients with and without a history of hypertension
复制标题
有或无高血压病史的患者冠状动脉搭桥术后各种生活质量评估的改善
DOI：
10.1097/00004872-199715090-00015
复制
发表时间：
1997
影响因子：
4.9
通讯作者：
J. Herlitz
中科院分区：
文献类型：
--
作者：
H. Sjöland;M. Hartford;K. Caidahl;B. Karlson;I. Wiklund;T. Karlsson;J. Herlitz
目的描述有高血压病史的患者与非高血压患者在冠状动脉旁路移植术(CABG)前和术后2年的生活质量(QOL)评估。方法选择1988~1991年间在瑞典西部地区行冠状动脉旁路移植术的患者。他们的生活质量是通过体力活动得分、诺丁汉健康概况和心理综合幸福指数来估计的。结果3份问卷均显示高血压患者和非高血压患者的生活质量在3个月时均有显著改善，且持续1年和2年。术后3个月，高血压病患者的身体活动评分和心理总体幸福感指数与非高血压患者相比，其生活质量改善不明显(P<；0.05)。冠状动脉旁路移植术两年后，在体力活动评分方面，高血压患者的改善不如非高血压患者明显(P<；0.01)。根据诺丁汉健康档案，高血压患者和非高血压患者在术后的每一次评估中改善情况相似。这三项指标的结果表明，高血压患者的生活质量比非高血压患者更差。然而，在同时考虑其他风险指标的多变量分析中，高血压病史并不是冠状动脉搭桥术后2年不良生活质量的独立风险指标。结论无论是高血压患者还是非高血压患者，冠脉搭桥术后患者的各项生活质量评价均有显著改善。高血压患者的改善程度往往不如非高血压患者，尤其是在术后3个月和体力活动方面。高血压患者的生活质量比非高血压患者差。然而，差异很小，主要可以用高血压以外的其他因素来解释。
Objective To describe various estimates of the quality of life (QOL) prior to and for 2 years after coronary artery bypass grafting (CABG) for patients with a history of hypertension compared with nonhypertensives. Methods Patients in western Sweden in whom CABG had been performed between 1988 and 1991 participated. Their QOL was estimated from the Physical Activity Score, the Nottingham Health Profile, and the Psychological General Well-being Index. Results All three questionnaires detected a significant improvement in QOL already at 3 months, which persisted at 1 and 2 years both for hypertensive and for nonhypertensive patients. With the Physical Activity Score and the Psychological General Well-being Index the improvement in QOL of hypertensive patients was less marked 3 months after the operation compared with that of nonhypertensives (P < 0.05). Two years after the CABG improvement was less marked for hypertensive patients than it was for nonhypertensive patients in terms of the Physical Activity Score (P < 0.01). With the Nottingham Health Profile the improvement was similar for hypertensive and nonhypertensive patients at each evaluation after the operation. With all three measures the results indicated that hypertensive patients had a worse QOL than did nonhypertensive patients. However, in a multivariate analysis considering other risk indicators simultaneously, a history of hypertension did not appear as an independent risk indicator for an adverse QOL 2 years after CABG. Conclusion There was a significant improvement in various QOL estimates after CABG both for hypertensive and for nonhypertensive patients. The degree of improvement tended to be less marked for hypertensive patients than it was for nonhypertensive patients, especially 3 months after the operation and concerning physical activities. Hypertensives had a worse QOL than did nonhypertensives. However, the differences were small and could mainly be explained in terms of factors other than hypertension.