Use of TSH response to TRH as an independent variable.
Use of TSH response to TRH as an independent variable.
复制标题
使用 TSH 对 TRH 的反应作为自变量。
DOI：
10.1176/ajp.140.6.700
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发表时间：
1983
期刊：
影响因子：
--
通讯作者：
PrangeJr,AJ
中科院分区：
文献类型：
--
作者：
Loosen,PT;Kistler,K;PrangeJr,AJ
在 35 名连续入院的男性中评估了促甲状腺素 (TSH) 对促甲状腺素释放激素 (TRH) 的反应。确定 TSH 钝化患者；他们与没有钝化的患者和正常受试者进行了比较。没有 TSH 钝化的患者的所有内分泌变量均正常。 TSH 钝化患者在 TRH 给药前后表现出 TSH（但催乳素正常）水平降低，尽管他们的甲状腺激素水平和皮质醇水平正常。身高、体重和体表面积与 TSH 钝化无关。钝化 TSH 反应的重测可靠性是可以接受的。
The thyrotropin (TSH) response to thyrotropin-releasing hormone (TRH) was assessed in 35 consecutive male admissions. Patients with TSH blunting were identified; they were compared with patients without blunting and with normal subjects. Patients without TSH blunting were normal as regards all endocrine variables. Patients with TSH blunting showed reduced TSH (but normal prolactin) levels before and after TRH administration, although their thyroid hormone levels and cortisol levels were normal. Height, weight, and body surface were unrelated to TSH blunting. The test-retest reliability of a blunted TSH response was acceptable.