Evaluation of serotypes of Streptococcus pneumoniae isolated from otitis media patients by multiplex polymerase chain reaction
Evaluation of serotypes of Streptococcus pneumoniae isolated from otitis media patients by multiplex polymerase chain reaction
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DOI：
10.1159/000091275
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发表时间：
2006-01-01
期刊：
影响因子：
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通讯作者：
Yamanaka, N
中科院分区：
文献类型：
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作者：
Billal, DS;Hotomi, M;Yamanaka, N
肺炎球菌性急性中耳炎的管理难度越来越大，同时抗微生物药物耐药菌株也在增加，这使得人们对肺炎球菌荚膜类型产生了很大的兴趣，以便通过疫苗进行有效的预防。多重聚合酶链反应是一种有价值的、快速的肺炎球菌荚膜分型方法。多重聚合酶链反应方法可准确检测从急性中耳炎患儿中分离的大多数血清型和血清组，从而确定定植模式，从而进一步影响肺炎球菌疫苗的使用。版权所有(c) 2006 S. Karger AG，巴塞尔。
The increasing difficulty in the management of pneumococcal acute otitis media in parallel with increases in antimicrobial-resistant strains has led to much interest in pneumococcal capsular types for the adoption of effective prevention by vaccines. This study shows that multiplex polymerase chain reaction is a valuable and expeditious method for the capsular typing of pneumococci. The multiplex polymerase chain reaction method accurately detects the majority of serotypes and serogroups frequently isolated from pediatric patients with acute otitis media, allowing the characterization of the colonization patterns for further implications of pneumococcal vaccines. Copyright (c) 2006 S. Karger AG, Basel.