The Correlation Between GPR30 and Clinicopathologic Variables in Breast Carcinomas
The Correlation Between GPR30 and Clinicopathologic Variables in Breast Carcinomas
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GPR30 与乳腺癌临床病理变量之间的相关性
DOI：
10.1177/153303460900800308
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发表时间：
2009-06-01
影响因子：
2.8
通讯作者：
Yu, Tinghe
中科院分区：
文献类型：
--
作者：
Tu, Gang;Hu, Dingrong;Yu, Tinghe
G蛋白偶联受体30（GPR 30）是一种新的膜雌激素受体。本研究旨在探讨乳腺癌组织中GPR 30、ER α、PR、C-erbB-2、p53、TNM分期和病理分级之间的相关性。对241例活检标本进行免疫组化检测，并进行相关性分析。GPR 30与ER α呈低度负相关（r=-0.144，P
The G-protein-coupled-receptor 30 (GPR30) is a new membrane estrogen receptor. The aim of the present study was to determine the correlations among GPR30, ER alpha, PR, C-erbB-2, p53, TNM stage, and pathologic grade in breast carcinomas. Two hundred forty-one biopsy specimens were evaluated with immunohistochemical assays, and then correlations were analyzed. Low negative correlations of GPR30 with ER alpha (r=-0.144, P