Enhancing Detection Sensitivity of ZnO-Based Infrared Plasmonic Sensors Using Capped Dielectric Ga2O3 Layers for Real-Time Monitoring of Biological Interactions
Enhancing Detection Sensitivity of ZnO-Based Infrared Plasmonic Sensors Using Capped Dielectric Ga2O3 Layers for Real-Time Monitoring of Biological Interactions
复制标题
使用盖帽电介质 Ga2O3 层提高 ZnO 基红外等离子传感器的检测灵敏度，实时监测生物相互作用
DOI：
10.1021/acsabm.0c00792
复制
发表时间：
2020
影响因子：
4.7
通讯作者：
H. Tabata
中科院分区：
文献类型：
--
作者：
Y. Kuranaga;H. Matsui;A. Ikehata;Y. Shimoda;M. Noiri;Y.L. Ho;J.J. Delaunay;Y. Teramura;H. Tabata
掺镓氧化锌(ZnO/Ga)层表面的表面等离子体共振作为红外波段的替代等离子体材料引起了人们极大的关注。我们通过在氧化锌表面等离子体反射器中引入薄介质层，显著改变了传感表面的电场和相应的衰减长度，从而进一步提高了氧化锌表面等离子体激活剂的检测极限，以监测生物相互作用。高介电常数Ga2O3层的存在提供了高波长灵敏度的ZnO-SPR，这是由于强限制电场所致。通过实时监测生物素和链霉亲和素分子之间的生物相互作用，验证了所提出的样品的优越传感能力。高介电常数介质层的引入有效地提高了检测灵敏度，从而可以观察生物相互作用。本文从等离子体应用的角度为基于氧化锌的生物光学检测技术的发展提供了有用的信息。
Surface plasmon resonances on Ga-doped ZnO (ZnO/Ga) layer surfaces (ZnO-SPRs) have attracted substantial attention as alternative plasmonic materials in the infrared range. We present further enhancement of the detection limits of ZnO-SPRs to monitor biological interactions by introducing thin dielectric layers into ZnO-SPRs, which remarkably modify the electric fields and the corresponding decay lengths on the sensing surfaces. The presence of a high-permittivity dielectric layer of Ga2O3provides high wavelength sensitivities of the ZnO-SPRs due to the strongly confined electric fields. The superior sensing capabilities of the proposed samples were verified by real-time monitoring of the biological interactions between biotin and streptavidin molecules. Introduction of the high-permittivity dielectric layer into ZnO-SPRs effectively enhances the detection sensitivity and therefore allowed for the observation of biological interactions. This paper provides useful information for the development of optical detection techniques for use in biological fields based on ZnO from the viewpoints of plasmonic applications.