Associations Between Postpartum Depression, Breastfeeding, and Oxytocin Levels in Latina Mothers
Associations Between Postpartum Depression, Breastfeeding, and Oxytocin Levels in Latina Mothers
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DOI：
10.1089/bfm.2016.0213
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发表时间：
2017-09-01
影响因子：
2.7
通讯作者：
Meltzer-Brody, Samantha
中科院分区：
文献类型：
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作者：
Lara-Cinisomo, Sandraluz;McKenney, Kathryn;Meltzer-Brody, Samantha
背景：产后抑郁症（PPD），往往与焦虑共病，是新妈妈的主要医疗并发症。拉丁裔患PPD的风险较高，这与早期停止母乳喂养有关。较低的血浆催产素（OT）水平也与非拉丁裔的PPD有关。这项试点研究探讨PPD，焦虑，母乳喂养，OT在Latinas.Materials和方法之间的关联：34拉丁人参加了在他们的妊娠晚期，并通过产后8周。在入组时收集人口统计学数据。在每个时间点（妊娠晚期，产后4周和8周）使用爱丁堡产后抑郁量表（EPDS）评估抑郁症。采用Spielberger状态-特质焦虑量表（STAI）和EPDS焦虑量表评估产后各时间点的焦虑状况。在产后4周和8周评估母乳喂养状况。在第8周，OT之前，期间和之后，10分钟的母乳喂养/奶瓶喂养会议从28名妇女谁完成了程序。提供描述性统计，并进行情绪和母乳喂养状态的比较。方差分析被用来探讨PPD，焦虑，母乳喂养状态和OT之间的关联。结果：只有不到三分之一的妇女在入学时感到沮丧。产前抑郁、产后抑郁和焦虑与早期母乳喂养停止显著相关（即，2个月内停止母乳喂养）（P < 0.05）。结论：产后8周患产后抑郁症和产后8周停止母乳喂养的产妇OT水平较低。未来的研究应调查较低的OT水平和早期停止母乳喂养对母婴健康的短期和长期影响。
Background: Postpartum depression (PPD), often comorbid with anxiety, is the leading medical complication among new mothers. Latinas have elevated risk of PPD, which has been associated with early breastfeeding cessation. Lower plasma oxytocin (OT) levels have also been associated with PPD in non-Latinas. This pilot study explores associations between PPD, anxiety, breastfeeding, and OT in Latinas.Materials and Methods: Thirty-four Latinas were enrolled during their third trimester of pregnancy and followed through 8 weeks postpartum. Demographic data were collected at enrollment. Depression was assessed using the Edinburgh Postnatal Depression Scale (EPDS) at each time point (third trimester of pregnancy, 4 and 8 weeks postpartum). The Spielberger State-Trait Anxiety Inventory (STAI) was administered postpartum and EPDS anxiety subscale was used to assess anxiety at each time point. Breastfeeding status was assessed at 4 and 8 weeks postpartum. At 8 weeks, OT was collected before, during, and after a 10-minute breast/bottle feeding session from 28 women who completed the procedures. Descriptive statistics are provided and comparisons by mood and breastfeeding status were conducted. Analyses of variance were used to explore associations between PPD, anxiety, breastfeeding status, and OT.Results: Just under one-third of women were depressed at enrollment. Prenatal depression, PPD, and anxiety were significantly associated with early breastfeeding cessation (i.e., stopped breastfeeding before 2 months) (p < 0.05). There was a significant interaction between early breastfeeding cessation and depression status on OT at 8 weeks postpartum (p < 0.05).Conclusions: Lower levels of OT were observed in women who had PPD at 8 weeks and who had stopped breastfeeding their infant by 8 weeks postpartum. Future studies should investigate the short- and long-term effects of lower OT levels and early breastfeeding cessation on maternal and child well-being.