Mfold web server for nucleic acid folding and hybridization prediction
Mfold web server for nucleic acid folding and hybridization prediction
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DOI：
10.1093/nar/gkg595
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发表时间：
2003-07-01
影响因子：
14.9
通讯作者：
Zuker, M
中科院分区：
文献类型：
--
作者：
Zuker, M
缩写为“mfold web server”，描述了万维网（WWW）上提供的一些密切相关的软件应用程序，用于预测单链核酸的二级结构。这个web服务器的目标是为科学界提供方便的RNA和DNA折叠和杂交软件。通过使用普遍可用的web gui（图形用户界面），服务器规避了该软件的可移植性问题。详细的输出，以带或不带可靠性信息的结构图、单链频率图和“能量点图”的形式，可用于单个序列的折叠。各种“批量”服务器提供的信息更少，但在更短的时间内，一次最多可以处理数百个序列。mfold web服务器的门户是http://www.bioinfo.rpi.edu/applications/mfold。这个URL将被称为“mfolroot”。
The abbreviated name, 'mfold web server', describes a number of closely related software applications available on the World Wide Web (WWW) for the prediction of the secondary structure of single stranded nucleic acids. The objective of this web server is to provide easy access to RNA and DNA folding and hybridization software to the scientific community at large. By making use of universally available web GUIs (Graphical User Interfaces), the server circumvents the problem of portability of this software. Detailed output, in the form of structure plots with or without reliability information, single strand frequency plots and 'energy dot plots', are available for the folding of single sequences. A variety of 'bulk' servers give less information, but in a shorter time and for up to hundreds of sequences at once. The portal for the mfold web server is http://www.bioinfo.rpi.edu/applications/mfold. This URL will be referred to as 'MFOLDROOT'.