A NOVEL SUBGROUP OF EXOGENOUS AVIAN-LEUKOSIS VIRUS IN CHICKENS
A NOVEL SUBGROUP OF EXOGENOUS AVIAN-LEUKOSIS VIRUS IN CHICKENS
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DOI：
10.1099/0022-1317-72-4-801
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发表时间：
1991-04-01
影响因子：
3.8
通讯作者：
THOULESS, ME
中科院分区：
文献类型：
--
作者：
PAYNE, LN;BROWN, SR;THOULESS, ME
从肉用型鸡中分离到一种新的鸡白血病病毒，该病毒具有广泛的宿主范围。 以HPRS-103株为原型的该病毒在鸡体内的致瘤性较低，但表现为外源性白血病病毒。 在五个肉类鸡系中的三个中发现了病毒的中和抗体，但在七个蛋鸡系中没有发现。 该病毒及其劳斯肉瘤病毒假型不能在哺乳动物细胞中复制或转化。
An avian leukosis virus with a wide host range belonging to a new subgroup for chickens was isolated from meat-type chicken lines. The virus, of which HPRS-103 strain is the prototype, was of low oncogenicity in chickens but appeared to behave like an exogenous leukosis virus. Neutralizing antibodies to the virus were found in three of five meat-type chicken lines, but not in seven layer lines. The virus and its Rous sarcoma virus pseudotype did not replicate in, or transform, mammalian cells.