Long-term Outcomes of One Stage Surgery Using Transanal Colorectal Tube for Acute Colorectal Obstruction of Stage II/III Distal Colon Cancer.
Long-term Outcomes of One Stage Surgery Using Transanal Colorectal Tube for Acute Colorectal Obstruction of Stage II/III Distal Colon Cancer.
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一级手术的长期结局，使用跨型结直肠管，用于II/III期远端结肠癌的急性结直肠梗阻。
DOI：
10.4143/crt.2018.059
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发表时间：
2019-04
影响因子：
4.6
通讯作者：
Joh T
中科院分区：
文献类型：
--
作者：
Okuda Y;Yamada T;Hirata Y;Shimura T;Yamaguchi R;Sakamoto E;Sobue S;Nakazawa T;Kataoka H;Joh T
由于经肛门结直肠管(TCT)置入的肿瘤学结果尚不清楚，这是一种治疗结直肠癌(CRC)合并急性结直肠梗阻(ACO)的内窥镜治疗方法，该研究分析了TCT置入对II/III期结直肠癌合并ACO的长期结果。对2007年1月至2011年12月在两家日本医院接受手术的连续II/III期结直肠癌患者的数据进行了回顾。一家医院进行了紧急手术，另一家医院进行了TCT放置，作为所有患有ACO的CRC的标准治疗。采用倾向性评分(PS)匹配的方法调整两组患者的基线特征。在754例远端II/III期大肠癌患者中，680例无ACO(非ACO组)，74例有ACO(ACO组)。两家医院之间的PS配对确定了非ACO组的234对和ACO组的23对。在非ACO组，两家机构的手术质量相当，总体生存期(OS)和无病生存期(DFS)无显著差异。在ACO组中，电切组的一期切除/吻合率高于手术组(87.0%vs.26.1%，p<；0.001)。在OS(5年OS，61.9%比51.5%；p=0.490)和DFS(5年DFS，45.9%比38.3%；p=0.658)方面，手术组和TCT组之间没有显著差异。TCT置入可以达到与急诊手术相似的长期效果，对于伴有ACO的远端II/III期结肠癌，一期切除/吻合率较高。
Since oncological outcomes of transanal colorectal tube (TCT) placement, an endoscopic treatment for colorectal cancer (CRC) with acute colorectal obstruction (ACO), remain unknown, this study analyzed long-term outcomes of TCT placement for stage II/III CRC with ACO. Data were retrospectively reviewed from consecutive patients with distal stage II/III CRC who underwent surgery between January 2007 and December 2011 at two Japanese hospitals. One hospital conducted emergency surgery and the other performed TCT placement as the standard treatment for all CRCs with ACO. Propensity score (PS) matching was used to adjust baseline characteristics between two groups. Among 754 patients with distal stage II/III CRC, 680 did not have ACO (non-ACO group) and 74 had ACO (ACO group). The PS matching between both hospitals identified 234 pairs in the non-ACO group and 23 pairs in the ACO group. In the non-ACO group, the surgical quality was equivalent between the two institutions, with no significant differences in overall survival (OS) and disease-free survival (DFS). In the ACO group, the rate of primary resection/anastomosis was higher in the TCT group than in the surgery group (87.0% vs. 26.1%, p < 0.001). No significant differences were noted between the surgery and the TCT groups in OS (5-year OS, 61.9% vs. 51.5%; p=0.490) and DFS (5-year DFS, 45.9% vs. 38.3%; p=0.658). TCT placement can achieve similar long-term outcomes to emergency surgery, with a high rate of primary resection/anastomosis for distal stage II/III colon cancer with ACO.
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影响因子：
3.4
作者：
Sjo, O. H.;Larsen, S.;Nesbakken, A.
通讯作者：
Nesbakken, A.
影响因子：
4.3
作者：
Ye, Guang-Yao;Cui, Zhe;Zhong, Ming
通讯作者：
Zhong, Ming
影响因子：
3.9
作者：
Tanaka, T;Furukawa, A;Sakamoto, T
通讯作者：
Sakamoto, T
影响因子：
9.6
作者：
McArdle, CS;McMillan, DC;Hole, DJ
通讯作者：
Hole, DJ
影响因子：
2.6
作者：
Alcantara, M.;Serra-Aracil, X.;Navarro, S.
通讯作者：
Navarro, S.