VOLTAGE-INDUCED CAPACITANCE RELAXATION OF LIPID BILAYER MEMBRANES - EFFECTS OF MEMBRANE COMPOSITION
VOLTAGE-INDUCED CAPACITANCE RELAXATION OF LIPID BILAYER MEMBRANES - EFFECTS OF MEMBRANE COMPOSITION
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DOI：
10.1016/0005-2736(76)90043-2
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发表时间：
1976-01-01
期刊：
影响因子：
--
通讯作者：
JANKO, K
中科院分区：
文献类型：
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作者：
BENZ, R;JANKO, K
研究了不同磷脂溶解在正烷烃中的黑色脂质膜的比容量。根据介电常数为 2.1 的电容计算，这些膜的碳氢化合物厚度在大多数情况下接近 5 nm。发黑后比容量随时间不恒定。它显示了每种脂质/溶剂系统的线性时间依赖性特征。测量跨膜电位对膜容量的影响。施加电压 10 秒后获得的容量变化程度很大程度上取决于膜的脂质成分和溶剂含量。膜的容量变化似乎主要是由厚度变化引起的，而不是由膜的面积增加引起的。
The specific capacity of black lipid membranes of different phospholipids dissolved in n-alkanes was investigated. The hydrocarbon thickness of these membranes, as calculated from the electric capacity with a dielectric constant of 2.1, was in most cases close to 5 nm. The specific capacity is not constant with time after blackening. It shows a linear time dependence characteristic for each lipid/solvent system. The influence of a transmembrane potential on the capacity of the membranes was measured. The extent of the capacity change, obtained 10 s after applying a voltage, was strongly dependent on the lipid composition and the solvent content of the membranes. The capacity change of the membranes seems to be caused mainly by a thickness change and not by an area increase of the membranes.