Associations of obesity measures with metabolic risk factors in a community-based population in Japan
Associations of obesity measures with metabolic risk factors in a community-based population in Japan
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DOI：
10.1253/circj.71.776
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发表时间：
2007-05-01
影响因子：
3.3
通讯作者：
Ueshima, Hirotsugu
中科院分区：
文献类型：
--
作者：
Nakamura, Yasuyuki;Turin, Tanvir C.;Ueshima, Hirotsugu
背景在社区人群中，肥胖指标（即体重指数（BMI）、腰围（WC）和腰臀比（WHR））与代谢危险因素的关系尚未得到很好的研究。方法与结果在本研究中，759名男性和1255名女性，年龄在30 ~ 79岁之间，无卒中或冠心病病史，按BMI-WHR、WC-WHR和BMI-WC的中位数进行二分类。检测4种代谢危险因素的累积（risk_sum）：高血压（>= 130/85 mmHg或正在接受降压治疗）；高甘油三酯（>= 170 mg/dl）；低高密度脂蛋白-胆固醇（< 40 mg/dl）；糖耐量受损（糖化血红蛋白>= 5.6%或接受降糖治疗）。BMI和WC在男性（r=0.871）和女性（r=0.874）中均有良好的相关性。所有3种肥胖测量都与代谢危险因素有关。BMI、WC和WHR预测男性风险总和>= 2的受试者-工作特征曲线下面积分别为0.683、0.709和0.700，女性分别为0.715、0.739和0.746。结论如果不能获得WC，可以用BMI代替WC。当测量腰围时，臀围也应该测量，因为腰臀比可能是衡量肥胖的最有价值的指标。
Background The association of obesity measures (ie, body mass index (BMI), waist circumference (WC) and waist-to hip ratio (WHR)) with metabolic risk factors in community-based populations has not been well studied.Methods and Results In the present study 759 men and 1,255 women aged between 30 and 79 years, without histories of stroke or coronary heart diseases, were dichotomized at the medians of BMI-WHR, WC-WHR and BMI-WC. The accumulation of 4 metabolic risk factors (risk_sum) were examined: high blood pressure (>= 130/85 mmHg or on antiltypertensive therapy); high triglycerides (>= 170 mg/dl); low high-density lipoprotein-cholesterol (< 40 mg/dl); and impaired glucose tolerance (hemoglobin A1c >= 5.6% or on antidiabetic therapy). BMI and WC correlated well in both men (r=0.871) and women (r=0.874). All 3 obesity measures related with the metabolic risk factors. The area under the receiver-operating characteristic curve for BMI, WC and WHR to predict the risk_sum >= 2 for men was 0.683, 0.709, and 0.700, respectively, and 0.715, 0.739, and 0.746, respectively, for women.Conclusions BMI maybe used instead of WC if the latter is not available. When WC is measured, hip circumference also should be measured because the WHR maybe the most valuable measure of obesity.