Mini mental state examination and the Addenbrooke's cognitive examination: Effect of education and norms for a multicultural population
Mini mental state examination and the Addenbrooke's cognitive examination: Effect of education and norms for a multicultural population
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DOI：
10.4103/0028-3886.32779
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发表时间：
2007-04-01
期刊：
影响因子：
2.7
通讯作者：
Sarma, Sankara P.
中科院分区：
文献类型：
--
作者：
Mathuranath, P. S.;Cherian, Joseph P.;Sarma, Sankara P.
目的：编制阿登布鲁克认知测验马拉雅拉姆适应量表(M ACE)和马来亚拉姆简易智力状态测验(M-MMSE)的人群常模。材料与方法：随机抽取社区认知正常老年人(n=519)进行教育分层常模。结果：获得4813名常模的有效数据(年龄68.5±7.1岁，文化程度7.9±5.4岁)。教育程度和年龄对MACE和M-MMSE均有显著影响，而性别对MACE和M-MMSE无显著影响。与年龄相比，教育对M-ACE的影响是7倍，对M-MMSE的影响是9倍。M-ACE(和M-MMSE)总分分别为42.8+/-9.8(14.9+/-3.1)、55.9+/-12.5(19.7+/-4.1)、62.6+/-11.4(21.9+/-3.7)和5-8(n=81)。77+/-10.2(25.7+/-2.4)，9-12(n=136)和83.4+/-7.2(26.7+/-1.6)；结论：在印度队列中，受教育程度对M-ACE和M-MMSE成绩的影响最大。M-ACE和M-MMSE的教育分层评分将为确定患者的认知状态提供更合适的手段。我们也感觉到，这些分数线将在印度各地发挥作用。
Objective: To derive population norms on the Malayalam adaptation of Addenbrooke's Cognitive Examination (M ACE) and the inclusive Malayalam mini mental state examination (M-MMSE).Materials and Methods: Education-stratified norms were obtained on randomly selected cognitively unimpaired community elders (n = 519).Results: Valid data on norms was available on 4813 subjects (age 68.5 +/- 7.1 and education 7.9 +/- 5.4). Education and age, but not gender had a significant effect on both MACE and M-MMSE. When compared to the effect of age, the effect of education was sevenfold more on the M-ACE and ninefold more on the M-MMSE. The mean composite score on the M-ACE (and the M-MMSE) was 42.8 +/- 9.8 (14.9 +/- 3.1) for those with 0 (n = 72), 55.9 +/- 12.5 (19.7 +/- 4.1) with 1- 4 (n = 96), 62.6 +/- 11.4 (21.9 +/- 3.7) with 5-8 (n = 81), 77 +/- 10.2 (25.7 +/- 2.4) with 9-12 (n = 136) and 83.4 +/- 7.2 (26.7 +/- 1.6) with > 12 (n = 103) years of formal education.Conclusions: Education has the most potent effect on performance on both M-ACE and M-MMSE in the Indian cohort. Education-stratified scores on the M-ACE and the M-MMSE, will provide a more appropriate means of establishing the cognitive status of patients. It is also our feeling that these cut-off scores will be useful across India.