Colonization with superantigen‐producing Staphylococcus aureus is associated with increased severity of atopic dermatitis
Colonization with superantigen‐producing Staphylococcus aureus is associated with increased severity of atopic dermatitis
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DOI：
10.1046/j.1365-2222.2000.00848.x
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发表时间：
2000-07
影响因子：
6.1
通讯作者：
Zollner;Wichelhaus;Hartung;Von Mallinckrodt;Wagner;Brade;Kaufmann
中科院分区：
文献类型：
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作者：
Zollner;Wichelhaus;Hartung;Von Mallinckrodt;Wagner;Brade;Kaufmann
特应性皮炎（AD）是一种慢性炎症性皮肤病，与已知产生具有超抗原（SAg）活性毒素的金黄色葡萄球菌在皮肤上定植有关。除了激活T细胞外，这些毒素在体外诱导T细胞皮肤归巢。这可能导致观察到的皮肤炎症的诱导或增强。
Atopic dermatitis (AD) is a chronic inflammatory skin disease associated with colonization of the skin with Staphylococcus aureus known to produce toxins with superantigen (SAg) activity. Besides T‐cell activation these toxins induce T‐cell skin homing in vitro. This may contribute to the observed induction or enhancement of skin inflammation.