Regional brain iron, ferritin and transferrin concentrations during iron deficiency and iron repletion in developing rats
Regional brain iron, ferritin and transferrin concentrations during iron deficiency and iron repletion in developing rats
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DOI：
10.1093/jn/127.10.2030
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发表时间：
1997-10-01
影响因子：
4.2
通讯作者：
Beard, JL
中科院分区：
文献类型：
--
作者：
Erikson, KM;Pinero, DJ;Beard, JL
年轻大鼠缺铁导致脑铁和铁蛋白浓度降低，转铁蛋白（Tf）浓度增加，以及从血浆池中摄取铁的速率增加。我们进行了两个实验，以确定是否脑铁，转铁蛋白和铁蛋白快速响应铁的补充，并确定是否大脑区域的反应不均匀。断奶雄性Sprague-Dawley大鼠喂食缺铁饮食（
Iron deficiency in young rats leads to a decrease in brain iron and ferritin concentrations, an increase in transferrin (Tf) concentration, and an increased rate of uptake of iron from the plasma pool. We conducted two experiments to determine whether brain iron, Tf and ferritin respond quickly to iron repletion and to determine whether brain regions respond heterogeneously. Weanling male Sprague-Dawley rats were fed an iron-deficient diet (