Role of integrins in cellular responses to mechanical stress and adhesion
Role of integrins in cellular responses to mechanical stress and adhesion
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DOI：
10.1016/s0955-0674(97)80125-1
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发表时间：
1997-10-01
影响因子：
7.5
通讯作者：
Chien, S
中科院分区：
文献类型：
--
作者：
Shyy, JYJ;Chien, S
Mechanical stresses are important environmental cues for both normal cellular functions and pathophysiological changes in conditions such as cardiac hypertrophy and atherosclerosis. There is increasing evidence that mechanotransduction processes in response to mechanical stresses share many common features with processes in cell adhesion, such as an increase in tyrosine phosphorylation of proteins in the focal adhesion sites. Recent findings suggest that integrins may function as mechanotransducers in cells.
