EFFECT OF CARBOXYL END GROUPS ON HYDROLYSIS OF POLYGLYCOLIC ACID
EFFECT OF CARBOXYL END GROUPS ON HYDROLYSIS OF POLYGLYCOLIC ACID
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DOI：
10.1002/pol.1985.170230709
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发表时间：
1985-01-01
影响因子：
--
通讯作者：
CASEY, DJ
中科院分区：
文献类型：
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作者：
HUFFMAN, KR;CASEY, DJ
采用六氟异丙醇中的染料相互作用分析法测定聚乙醇酸（PGA）的末端羧基。在37°C下，纯化PGA在水中的非均相水解速率显示出在高于12 meq/kg的水平下对羧基端基浓度的一级依赖性。熔融PGA与四芳基原碳酸酯或三芳基烯酮亚胺的反应得到羧基水平低至1 meq/kg的封端PGA。这些样品比未处理的PGA更耐水解，尽管在较低的羧基水平下初始速率增加。
Dye interaction analysis in hexafluoroisopropanol was used to determine end carboxyl groups in polyglycolic acid (PGA). The rate of heterogeneous hydrolysis of purified PGA in water at 37°C shows a first‐order dependence on carboxyl end group concentration at levels above 12 meq/kg. Reaction of molten PGA with a tetraarylorthocarbonate or a triarylketenimine gave end‐capped PGA with carboxyl levels as low as 1 meq/kg. These samples were somewhat more resistant to hydrolysis than untreated PGA despite an increased initial rate at the lower carboxyl levels.