MRI evaluation of white matter recovery after brain injury.
MRI evaluation of white matter recovery after brain injury.
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DOI：
10.1161/strokeaha.110.595629
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发表时间：
2010-10
期刊：
影响因子：
8.3
通讯作者：
Chopp M
中科院分区：
文献类型：
--
作者：
Jiang Q;Zhang ZG;Chopp M
我们讨论使用磁共振成像（MRI）在检测和分期脑损伤后白质重组与不神经修复治疗。基于弥散张量MRI （DTI）方法的变化，我们证明了MRI可以检测脑损伤后的白质重塑。此外，我们证明了q空间DTI可以检测早期轴突重构，其中包括随机定向交叉轴突。利用常规DTI和q空间DTI获得的信息，可以对脑损伤后的脑白质进行重构。
We discuss the use of magnetic resonance imaging (MRI) in detecting and staging white matter reorganization after brain injury with and without neurorestorative treatment. Based on variations of diffusion tensor MRI (DTI) methodology, we demonstrate that MRI can detect white matter remodeling after brain injury. In addition we demonstrate that Q-space DTI can detect early stage axonal remodeling which involves randomly oriented crossing axons. With the information obtained from conventional and Q-space DTI, it is possible to stage white matter remodeling after brain injury.