Subcutaneous Panniculitic-Like T-Cell Lymphoma and Other Primary Cutaneous Lymphomas with Prominent Subcutaneous Tissue Involvement

Subcutaneous Panniculitic-Like T-Cell Lymphoma and Other Primary Cutaneous Lymphomas with Prominent Subcutaneous Tissue Involvement
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DOI:
10.1016/j.det.2008.05.008
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发表时间:
2008-10-01
影响因子:
2.4
通讯作者:
Pujol, Ramon M.
Pujol, Ramon M.
中科院分区:
医学2区
文献类型:
--
作者:
Gallardo, Fernando;Pujol, Ramon M.

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皮下T细胞淋巴瘤的概念定义为一组减少的原发性皮肤淋巴瘤,其形态学特征为突出或仅累及皮下组织。皮下脂膜样T细胞淋巴瘤是原发性皮肤T细胞淋巴瘤的一种罕见亚型,临床上类似脂膜炎。临床过程通常是长期的复发性皮损,但很少有早期的皮外播散。本文回顾这组罕见且异质性的原发性皮肤淋巴瘤的临床、组织病理学、免疫表型及演化特征。
The concept of subcutaneous T-cell lymphoma defines a reduced group of primary cutaneous lymphomas characterized morphologically by a prominent or exclusive subcutaneous tissue involvement. Subcutaneous panniculitic-like T-cell lymphoma is a rare subtype of primary cutaneous T-cell lymphoma clinically mimicking panniculitis. The clinical course is usually protracted with recurrent cutaneous lesions but rarely with early extracutaneous dissemination. The clinical, histopathologic, immunophenotypic, and evolutive features of this heterogeneous and rare group of primary cutaneous lymphomas are reviewed.