The cutaneous reaction to staphylococcal protein A in normal subjects and patients with atopic dermatitis or psoriasis

The cutaneous reaction to staphylococcal protein A in normal subjects and patients with atopic dermatitis or psoriasis
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正常人和特应性皮炎或牛皮癣患者对葡萄球菌蛋白 A 的皮肤反应

DOI:
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发表时间:
1985
影响因子:
10.3
通讯作者:
W. Noble
W. Noble
中科院分区:
医学1区
文献类型:
--
作者:
M. White;W. Noble

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在健康志愿者和特应性皮炎和牛皮癣患者中进行葡萄球菌细胞壁成分蛋白A的皮内测试产生了一系列反应,但在所有组中都有立即的好转和闪光反应。随后的红斑有明显的个体差异,但特应性皮炎患者在15分钟和24小时的红斑比正常或银屑病患者少。银屑病患者在48小时出现最大的红斑反应。
Intradermal testing with the staphylococcal cell wall component, protein A, in healthy volunteers and in patients with atopic dermatitis and psoriasis produced a range of responses but in all groups there was an immediate weal and flare response. There was marked individual variation in subsequent erythema, but the patients with atopic dermatitis had less erythema at 15 min and 24h than normal or psoriatic individuals. The greatest erythematous reaction at 48h was seen in patients with psoriasis.