Intercellular signaling and signal transduction in C. elegans.
Intercellular signaling and signal transduction in C. elegans.
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秀丽隐杆线虫的细胞间信号传导和信号转导。
DOI：
10.1146/annurev.ge.27.120193.002433
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发表时间：
1993
影响因子：
11.1
通讯作者：
Sternberg,PW
中科院分区：
文献类型：
--
作者：
Sternberg,PW
Intercellular signaling and signal transduction underlie most aspects of development and behavior. To understand any specific case we must identify the ligands, receptors and transducers, as well as regulators that modulate the activity of the signaling pathway. To understand more general aspects of signaling, we have to address the questions: To what extent are there modular signaling pathways, ie pathways that act as coherent units? How many such pathways are there? What factors affect the action of a universal pathway in particular cases? How widely is a given component or pathway used? How are the effects of multiple signaling pathways integrated? Here I discuss the use of Caenorhabditis elegans molecular genetics to study problems of intercellular signaling and signal transduction.
