Prevalence and Incidence Rates of Dementia and Cognitive Impairment No Dementia in the Mexican Population: Data From the Mexican Health and Aging Study
Prevalence and Incidence Rates of Dementia and Cognitive Impairment No Dementia in the Mexican Population: Data From the Mexican Health and Aging Study
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DOI：
10.1177/0898264311421199
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发表时间：
2011-10-01
影响因子：
2.8
通讯作者：
Miguel Gutierrez, Luis
中科院分区：
文献类型：
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作者：
Mejia-Arango, Silvia;Miguel Gutierrez, Luis
目的：评估墨西哥人群中痴呆症和非痴呆性认知损害(CIND)的患病率和发病率。方法：MHAS研究是一项关于墨西哥健康和老龄化的前瞻性小组研究，有代表全国800万参与者的7000名老年人参加。通过对痴呆患者的认知和日常生活活动能力的测量，在基线和随访时确定患者和CIND。计算了总体发病率和性别、年龄和教育程度的特异率。结果：痴呆和CIND的患病率分别为6.1%和28.7%。痴呆症发病率为27.3/1000人年，CIND发病率为223/1000人年。痴呆和CIND的患病率随着年龄的增长而增加，随着文化程度的提高而降低；性别对年龄阶层的影响存在差异。高血压、糖尿病和抑郁是痴呆症的危险因素，但不是CIND的危险因素。讨论：这些数据提供了对墨西哥人口中痴呆症和认知障碍的患病率和发病率的估计，以预测未来的负担。
Objective: To estimate the prevalence and incidence of dementia and cognitive impairment without dementia (CIND) in the Mexican population. Method: The MHAS study is a prospective panel study of health and aging in Mexico with 7,000 elders that represent eight million participants nationally. Using measurements of cognition and activities of daily living of dementia cases and CIND were identified at baseline and follow-up. Overall incidence rates and specific rates for sex, age, and education were calculated. Results: Prevalence was 6.1% and 28.7% for dementia and CIND, respectively. Incidence rates were 27.3 per 1,000 person-years for dementia and 223 per 1,000 persons-year for CIND. Rates of dementia and CIND increased with advancing age and decreased with higher educational level; sex had a differential effect depending on the age strata. Hypertension, diabetes, and depression were risk factors for dementia but not for CIND. Discussion: These data provide estimates of prevalence and incidence of dementia and cognitive impairment in the Mexican population for projection of future burden.