Delirium detection by a novel bispectral electroencephalography device in general hospital.
Delirium detection by a novel bispectral electroencephalography device in general hospital.
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DOI：
10.1111/pcn.12783
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发表时间：
2018-12
影响因子：
11.9
通讯作者：
Cromwell JW
中科院分区：
文献类型：
--
作者：
Shinozaki G;Chan AC;Sparr NA;Zarei K;Gaul LN;Heinzman JT;Robles J;Yuki K;Chronis TJ;Ando T;Wong T;Sabbagh S;Weckmann MT;Lee S;Yamada T;Karam MD;Noiseux NO;Shinozaki E;Cromwell JW
谵妄在老年住院病人中是常见和危险的;然而，它被诊断不足，因此治疗不足。本研究旨在测试具有双通道（双频谱）脑电图（EEG）的无创床旁设备用于医院谵妄筛查的诊断特征。对入住爱荷华州大学医院和诊所的患者进行临床评估、重症监护室混乱评估方法和谵妄评定量表评估谵妄的存在。随后，我们在住院期间从手持式脑电图设备获得了10分钟的双谱脑电图（BSEEG）记录。我们进行了功率谱密度分析，以区分这些患者与无谵妄。最初，45名受试者被用作测试数据集以建立临界值。BSEEG指数被确定为谵妄的重要指标，灵敏度为80%，特异性为87.7%。另外一个包含24名患者的独立验证数据集证实了该方法的有效性，灵敏度为83.3%，特异性为83.3%。在这项初步研究中，BSEEG方法能够区分谵妄患者和非谵妄患者。我们的数据显示了这项技术在医院进行谵妄大规模筛查的可行性。
Delirium is common and dangerous among elderly inpatients; yet, it is underdiagnosed and thus undertreated. This study aimed to test the diagnostic characteristics of a noninvasive point-of-care device with two-channel (bispectral) electroencephalography (EEG) for the screening of delirium in the hospital. Patients admitted to the University of Iowa Hospitals and Clinics were assessed for the presence of delirium with a clinical assessment, the Confusion Assessment Method for Intensive Care Unit and Delirium Rating Scale. Subsequently, we obtained a 10-min bispectral EEG (BSEEG) recording from a hand-held electroencephalogram device during hospitalization. We performed power spectral density analysis to differentiate between those patients with and without delirium. Initially 45 subjects were used as a test dataset to establish a cut-off. The BSEEG index was determined to be a significant indicator of delirium, with sensitivity 80% and specificity 87.7%. An additional independent validation dataset with 24 patients confirmed the validity of the approach, with a sensitivity of 83.3% and specificity of 83.3%. In this pilot study, the BSEEG method was able to distinguish delirious patients from non-delirious patients. Our data showed the feasibility of this technology for mass screening of delirium in the hospital.
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影响因子：
158.5
作者：
Inouye, SK;Bogardus, ST;Cooney, LW
通讯作者：
Cooney, LW
CAM-S：在2个队列中del妄严重性的新评分系统的开发和验证。
影响因子：
39.2
作者：
Inouye SK;Kosar CM;Tommet D;Schmitt EM;Puelle MR;Saczynski JS;Marcantonio ER;Jones RN
通讯作者：
Jones RN
影响因子：
168.9
作者：
Inouye, Sharon K.;Westendorp, Rudi G. J.;Saczynski, Jane S.
通讯作者：
Saczynski, Jane S.
影响因子：
10.7
作者：
Doi, M;Gajraj, RJ;Kenny, GNC
通讯作者：
Kenny, GNC
影响因子：
5.7
作者：
Kuczmarska, Aleksandra;Ngo, Long H.;Marcantonio, Edward R.
通讯作者：
Marcantonio, Edward R.