Effective palliative radiofrequency ablation for tumors causing pain, numbness and motor function disorders: case series.
Effective palliative radiofrequency ablation for tumors causing pain, numbness and motor function disorders: case series.
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DOI：
10.1186/1756-0500-7-765
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发表时间：
2014-10-28
影响因子：
1.8
通讯作者：
Miki Y
中科院分区：
文献类型：
--
作者：
Hamamoto S;Matsuoka T;Okuma T;Yamamoto A;Hamuro M;Miki Y
我们提出了一个病例系列的姑息性射频消融（RFA）的肿瘤，导致解决疼痛和运动功能障碍。RFA广泛用于各种器官的肿瘤，并且经常报告良好的结果。有一些报告称RFA是作为姑息治疗进行的，但也有一些报告称RFA是作为姑息治疗对肺肿瘤进行的。该病例系列包括两例病例，骶骨和肺部肿瘤的姑息性RFA。该病例系列的结果表明，姑息性RFA可有效改善患者的症状。案例1.一位64岁的日本女性，她的骶骨软骨病，她的左腿疼痛和跛行。虽然进行了手术、放射治疗和GS-TAE（明胶海绵经动脉栓塞，通过L5腰动脉），但肿瘤的大小增加，导致疼痛和跛行。对骶骨肿瘤进行了RFA，这些症状在手术后一年消退。案例2.一位68岁的日本男性，左肺尖部有平滑肌肉瘤，主诉左上肢疼痛及运动功能障碍。纵隔平滑肌肉瘤手术后出现胸膜播散。虽然接受放射线治疗及二次手术，但二次手术后左肺尖肿瘤增大，左上肢疼痛及麻木。对左肺肿瘤进行了RFA，RFA后3个月症状消退。RFA是一种有效的姑息治疗，当常规姑息治疗（如手术、放疗和化疗）困难或禁忌时，有可能挽救患者的肿瘤症状。
We present a case series of a palliative radiofrequency ablation (RFA) for the tumors that lead to the resolution of pain and motor function disorders. RFA is widely used on tumors in various organs and often reported in good outcome. There are some reports that RFA was performed as a palliative treatment but a few reports of RFA that performed for lung tumor as a palliative treatment. This case series includes two cases, palliative RFA for a sacrum and a lung tumor. The results of this case series presented that a palliative RFA is effective in improving the symptoms of patients. Case 1. A 64-year-old Japanese woman with a chordoma at her sacrum presented with pain in her left leg and claudication. Though operations, radiation therapy and GS-TAE (gelatin sponge–transarterial embolization, via the L5 lumbar artery) were performed, the size of the tumor leading pain and claudication increased. RFA was performed for the sacral tumor, and these symptoms resolved one year after the procedure. Case 2. A 68-year-old Japanese man with a leiomyosarcoma at the apex of left lung presented with pain and motor function disorders of the left upper limb. Dissemination in the pleura was appeared after the operation for a leiomyosarcoma at the mediastinum. Though radiation therapy and a second operation were performed, the tumor at the apex of the left lung increased and pain and numbness of the left upper limb were appeared after the second operation. RFA was performed for the left lung tumor, and the symptoms resolved 3 months after RFA. RFA is effective as a palliative treatment and has a potential to salvage the patients from the symptoms of the tumors when conventional palliative treatments such as surgery, radiation therapy, and chemotherapy are difficult or contraindicated.