Ethiopians and Khoisan share the deepest clades of the human Y-chromosome phylogeny
Ethiopians and Khoisan share the deepest clades of the human Y-chromosome phylogeny
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DOI：
10.1086/338306
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发表时间：
2002-01-01
影响因子：
9.8
通讯作者：
Underhill, PA
中科院分区：
文献类型：
--
作者：
Semino, O;Santachiara-Benerecetti, AS;Underhill, PA
126埃塞俄比亚和139塞内加尔的Y染色体的遗传结构进行了调查的30个诊断双等位基因标记从世界各地的Y染色体系谱的层次分析。目前的研究表明，（1）只有埃塞俄比亚人与科伊桑人共享最深的人类Y染色体分支（非洲特有的第一和第二组），但具有非常不同的单倍型的剧目;（2）大多数埃塞俄比亚人和几乎所有的塞内加尔人属于第三组，其前身被认为是参与第一次迁移出非洲;（3）埃塞俄比亚人的Y染色体属于第六、第八和第九组，这可以解释为从亚洲返回。第一个观察结果证实了科萨人和科伊桑人之间的祖先亲缘关系，这一点先前已被考古学和遗传学发现所证实。
The genetic structure of 126 Ethiopian and 139 Senegalese Y chromosomes was investigated by a hierarchical analysis of 30 diagnostic biallelic markers selected from the worldwide Y-chromosome genealogy. The present study reveals that (1) only the Ethiopians share with the Khoisan the deepest human Y-chromosome clades (the African-specific Groups I and II) but with a repertoire of very different haplotypes; (2) most of the Ethiopians and virtually all the Senegalese belong to Group III, whose precursor is believed to be involved in the first migration out of Africa; and (3) the Ethiopian Y chromosomes that fall into Groups VI, VIII, and IX may be explained by back migrations from Asia. The first observation confirms the ancestral affinity between the Ethiopians and the Khoisan, which has previously been suggested by both archaeological and genetic findings.