Ultrasound Elastography: Review of Techniques and Clinical Applications.
Ultrasound Elastography: Review of Techniques and Clinical Applications.
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DOI：
10.7150/thno.18650
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发表时间：
2017
期刊：
影响因子：
12.4
通讯作者：
Willmann JK
中科院分区：
文献类型：
--
作者：
Sigrist RMS;Liau J;Kaffas AE;Chammas MC;Willmann JK
近年来，基于弹性成像技术的组织力学性能的非侵入性评估受到了极大的关注。这些技术利用各种病理中改变的软组织弹性来产生可用于诊断目的的定性和定量信息。在专用成像模式下采集测量值，该模式可以检测响应于所施加的机械力（压缩波或剪切波）的组织硬度。基于超声的方法由于其许多固有的优点而特别令人感兴趣，例如包括在床边的广泛可用性和相对低的成本。已经开发了几种使用不同激励方法的超声弹性成像技术。一般来说，这些可以被分类为使用内部或外部压缩刺激的应变成像方法，以及使用超声生成的行进剪切波刺激的剪切波成像。虽然超声弹性成像在肝纤维化的非侵入性评估中显示出有希望的结果，但在乳腺、甲状腺、前列腺、肾脏和淋巴结成像中的新应用正在出现。在这里，我们回顾了超声弹性成像的基本原理，基础物理和局限性，并总结了其目前的临床应用和正在进行的各种临床应用的发展。
Elastography-based imaging techniques have received substantial attention in recent years for non-invasive assessment of tissue mechanical properties. These techniques take advantage of changed soft tissue elasticity in various pathologies to yield qualitative and quantitative information that can be used for diagnostic purposes. Measurements are acquired in specialized imaging modes that can detect tissue stiffness in response to an applied mechanical force (compression or shear wave). Ultrasound-based methods are of particular interest due to its many inherent advantages, such as wide availability including at the bedside and relatively low cost. Several ultrasound elastography techniques using different excitation methods have been developed. In general, these can be classified into strain imaging methods that use internal or external compression stimuli, and shear wave imaging that use ultrasound-generated traveling shear wave stimuli. While ultrasound elastography has shown promising results for non-invasive assessment of liver fibrosis, new applications in breast, thyroid, prostate, kidney and lymph node imaging are emerging. Here, we review the basic principles, foundation physics, and limitations of ultrasound elastography and summarize its current clinical use and ongoing developments in various clinical applications.