Characteristics of intramucosal gastric carcinoma with lymph node metastatic disease
Characteristics of intramucosal gastric carcinoma with lymph node metastatic disease
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DOI：
10.1111/j.1365-2559.2004.01870.x
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发表时间：
2004-05-01
期刊：
影响因子：
6.4
通讯作者：
Rhee, JC
中科院分区：
文献类型：
--
作者：
Song, SY;Park, S;Rhee, JC
目的：早期胃癌（EGC）治疗策略的最新趋势是尽量减少外科手术，例如内镜下粘膜切除术和腹腔镜部分切除术。在最小的手术中可能无法完全切除区域淋巴结，这可能会降低治愈的机会。因此，必须能够预测淋巴结状态并仔细选择粘膜切除候选者。方法和结果：我们研究了淋巴结状态与各种病理参数之间的关系，包括宏观外观、位置、大小、分化、是否存在溃疡、血管分布、是否存在胃炎囊性深部腺体增殖、粘膜肌层破坏和 侵入粘膜肌层，使用 40 个淋巴结阳性和 80 个淋巴结阴性肿瘤的年龄和性别匹配样本来定义粘膜内 EGC 的特征。组织学分化（P
Aim: Recent trends in treatment strategy for early gastric cancer (EGC) are towards minimal surgical procedures, such as endoscopic mucosal resection and laparoscopic partial resection. There is a possibility of incomplete removal of regional lymph nodes in minimal procedures, which may subsequently decrease the chance of a cure. Therefore, it is essential to be able to predict lymph node status and to make careful selection of candidates for mucosal resection.Methods and results: We studied the relationship between lymph node status and various pathological parameters including macroscopic appearance, location, size, differentiation, presence of ulceration, vascularity, presence of gastritis cystica profunda-like glandular proliferation, disruption of the muscularis mucosae and invasion into the muscularis mucosae, using age- and sex-matched samples of 40 node-positive and 80 node-negative tumours to define the characteristics of intramucosal EGCs. Histological differentiation (P