Highly biocompatible jujube polysaccharide-stabilized palladium nanoparticles with excellent catalytic performance
Highly biocompatible jujube polysaccharide-stabilized palladium nanoparticles with excellent catalytic performance
复制标题
高度生物相容性的枣多糖稳定的钯纳米粒子，具有优异的催化性能
DOI：
10.1039/c9nj00950g
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发表时间：
2019-05-28
影响因子：
3.3
通讯作者：
Kang, Jianxin
中科院分区：
文献类型：
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作者：
Guo, Xiaolei;Zhang, Jin;Kang, Jianxin
稳定且生物相容的钯纳米颗粒（Pd NP）催化剂的开发引起了人们的极大兴趣。在本研究中，首次采用枣多糖（JP）作为还原剂和稳定剂，通过绿色方法制备了Pd NPs。 JP稳定的钯纳米颗粒（Pd-n-JP NPs）表现出尺寸小、稳定性高、生物相容性好和优异的催化效率。 Pd-50-JP NP 在宽 pH 范围 (4-9) 的溶液中表现出长达两周的高稳定性。 Pd-50-JP NPs 在高达 400 g mL(-1) 的高浓度下对 HeLa 细胞表现出可忽略不计的细胞毒性。此外，Pd-n-JP NPs 在硼氢化钠 (NaBH4) 存在下对 4-硝基苯酚 (4-NP) 的还原表现出优异的催化活性。 Pd-50-JP NPs的归一化速率常数(k(nor))和周转频率(TOF)分别高达38.4 s(-1) mM(-1)和4455 h(-1)。所制备的Pd-n-JP NPs未来将在生物相关催化领域具有多种潜在应用。
The development of stable and biocompatible palladium nanoparticles (Pd NPs) catalysts has been drawing great interest. In this study, Pd NPs were prepared through a green method, where jujube polysaccharide (JP) was employed as both reducing and stabilizing agents for the first time. The JP stabilized palladium nanoparticles (Pd-n-JP NPs) displayed small size, high stability, good biocompatibility and excellent catalytic efficiency. Pd-50-JP NPs showed high stability up to two weeks in solutions of a wide pH range (4-9). Pd-50-JP NPs showed negligible cytotoxicity against HeLa cells at a high concentration of up to 400 g mL(-1). Furthermore, Pd-n-JP NPs showed excellent catalytic activity for reduction of 4-nitrophenol (4-NP) in the presence of sodium borohydride (NaBH4). The normalized rate constant (k(nor)) and turnover frequency (TOF) of Pd-50-JP NPs were as high as 38.4 s(-1) mM(-1) and 4455 h(-1), respectively. The prepared Pd-n-JP NPs will have various potential applications in bio-related catalysis in the future.