Mutans streptococci oral colonization in 12-30-month-old Brazilian children over a one-year follow-up period
Mutans streptococci oral colonization in 12-30-month-old Brazilian children over a one-year follow-up period
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DOI：
10.1111/j.1752-7325.2001.tb03384.x
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发表时间：
2001-06-01
影响因子：
2.3
通讯作者：
Mayer, MPA
中科院分区：
文献类型：
--
作者：
Mattos-Graner, RO;Corrêa, MSNP;Mayer, MPA
目的：对在提供富含蔗糖饮食的学校托儿所就读的 12 至 30 个月大的儿童进行一年的随访，调查变形链球菌的感染水平。方法：从 101 名儿童的基线和一年随访后获得的变形链球菌口腔水平，按基线时的年龄、牙齿数量、饮食习惯和可见菌斑的存在情况进行比较。将研究期间变形链球菌水平的基线预测因子和变化与一年后的龋齿发生率进行比较。 结果：随访期间变形链球菌水平的波动与饮食习惯或可见牙菌斑的存在无关。一年后，12 至 24 个月的儿童中变形链球菌水平有所上升，而 25 至 30 个月的儿童中，在研究期间变形链球菌水平下降的比例明显更高。多元逻辑回归分析表明，基线时高水平的变形链球菌（大于或等于100 cfu）与较高的龋齿增量相关，而变形链球菌的减少与龋齿发生率呈负相关。结论：我们的数据表明，尽管早期有变形链球菌感染和大量接触蔗糖，但变形链球菌在 2 岁后可能会达到相对稳定的水平。早期变形链球菌的大量定植与儿童期极高的龋齿发病率有关，而变形链球菌水平的降低可能与龋齿活动的减少有关。
Objectives: The infection levels of mutans streptococci were investigated during a one-year follow-up in children aged 12 to 30 months attending school nurseries where a sucrose-rich diet was provided. Methods: Oral levels of mutans streptococci obtained from 101 children at baseline and after a one-year follow-up were compared by age, number of teeth, feeding habits, and presence of visible plaque at baseline. Baseline predictors and changes in mutans streptococci levels during the study were compared to caries incidence after one year Results: Fluctuations in mutans streptococci levels during the follow-up period were not related to feeding habits or presence of visible plaque. Mutans streptococci levels increased after one year among children aged 12 to 24 months, while a significantly higher proportion of those aged 25-30 months showed a decrease in mutans streptococci levels during the study. Multiple logistic regression analysis suggested that high levels of mutans streptococci (greater than or equal to 100 cfu) at baseline were associated with a higher caries increment, while reduction in mutans streptococci was negatively associated with caries incidence. Conclusions: Our data suggest that despite early mutans streptococci infection and high exposure to sucrose, mutans streptococci may achieve relatively stable levels after 2 years of age. Heavy colonization by mutans streptococci in an early age was related to an extremely high caries incidence during childhood, while decreasing levels of mutans streptococci can be associated to the decrease in caries activity.