Rhabdomyosarcoma of the head and neck in children
Rhabdomyosarcoma of the head and neck in children
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儿童头颈部横纹肌肉瘤
DOI：
10.1097/00006534-198509000-00098
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发表时间：
1984
期刊：
影响因子：
--
通讯作者：
R. Parker
中科院分区：
文献类型：
--
作者：
M. Selch;R. Parker
介绍了 17 名患有头部和颈部横纹肌肉瘤的儿童。中位随访时间为2年3个月，目前11名患者存活，7名患者无病生存，11名患者实现局部控制。在 13 名 III 组患者中，活检后接受放疗和化疗，其中 7 名患者存活，4 名患者无疾病，8 名患者实现局部控制。在由 9 名患有累及头颈部多个部位的肿瘤的 III 组患者组成的亚组中，4 名患者存活，2 名患者无疾病，6 名患者实现局部控制。在I-II组的四名患者中，三名患者实现了局部控制，目前所有患者均存活。长期并发症包括三名患者的面部骨骼发育不全和三名患者的白内障。初次放疗和化疗可以局部控制头颈部横纹肌肉瘤，同时避免与手术消融相关的功能和美容后遗症。
SEVENTEEN CHILDREN WITH RHABDOMYOSARCOMA arising in the head and neck are presented. With a median follow-up of 2 years 3 months, 11 patients are currently living, seven patients are alive free of disease, and local control was achieved in 11 patients. Of 13 group III patients managed with irradiation and chemotherapy following biopsy, seven patients are alive, with four patients free of disease, and local control achieved in eight patients. In a subgroup of nine group III patients with tumor involving multiple head and neck sites, four patients are alive, with two patients free of disease, and local control achieved in six patients. In four groups I-II patients, local control was achieved in three, and all patients are currently living. Long-term complications include facial bone hypoplasia in three patients and cataracts in three patients. Primary irradiation and chemotherapy can locally control rhabdomyosarcoma of the head and neck, while avoiding the functional and cosmetic sequelae associated with surgical ablation.