Investigation of intraoperative brain deformation using a 1.5-t interventional MR system: Preliminary results
Investigation of intraoperative brain deformation using a 1.5-t interventional MR system: Preliminary results
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DOI：
10.1109/42.736050
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发表时间：
1998-10-01
影响因子：
10.6
通讯作者：
Truwit, CL
中科院分区：
文献类型：
--
作者：
Maurer, CR;Hill, DLG;Truwit, CL
我们所知道的所有图像引导神经外科系统都假设头部及其内容物表现为刚体。测量术中脑变形（脑移位）对于提供图像引导手术系统应用精度的指示非常重要，同时也为开发和验证非刚性配准算法以纠正此类变形提供数据。我们正在收集高场（1.5 T）介入磁共振（MR）扫描仪中接受神经外科手术的患者的数据。术前、术中、手术结束时，患者插管躺在手术台上，采集高对比度、高分辨率梯度回波MR图像体积。在本文中，我们报告了6例患者的初步结果：1例徒手活检，1例立体定向功能手术和4例切除。我们通过检查阈值边界叠加和差分图像以及测量心室容积来研究术中脑变形，我们还提出了使用非刚性配准算法量化变形的初步结果。我们发现有些病例比其他病例有更大的变形，而且，无论手术方式如何，中线、幕、手术对侧半球和同侧结构几乎没有变形，除了那些在病变1厘米内或在手术部位上方的结构。
All image-guided neurosurgical systems that we are aware of assume that the head and its contents behave as a rigid body. It is important to measure intraoperative brain deformation (brain shift) to provide some indication of the application accuracy of image-guided surgical systems, and also to provide data to develop and validate nonrigid registration algorithms to correct for such deformation. We are collecting data from patients undergoing neurosurgery in a high-field (1.5 T) interventional magnetic resonance (MR) scanner. High-contrast and high-resolution gradient-echo MR image volumes are collected immediately prior to surgery, during surgery, and at the end of surgery,,vith the patient intubated and lying on the operating table in the operative position. In this paper we report initial results from six patients: one freehand biopsy, one stereotactic functional procedure, and four resections. We investigate intraoperative brain deformation by examining threshold boundary overlays and difference images and by measuring ventricular volume, We also present preliminary results obtained using a nonrigid registration algorithm to quantify deformation. We found that some cases had much greater deformation than others, and also that, regardless of the procedure, there was very little deformation of the midline, the tentorium, the hemisphere contralateral to the procedure, and ipsilateral structures except those that are within 1 cm of the lesion or are gravitationally above the Surgical site.