Pilot Study of Caffeine Abstinence for Control of Chronic Glucose in Type 2 Diabetes.

Pilot Study of Caffeine Abstinence for Control of Chronic Glucose in Type 2 Diabetes.
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戒断咖啡因控制 2 型糖尿病慢性血糖的初步研究。

DOI:
10.1089/jcr.2012.0003
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发表时间:
2012
期刊:
Journal of caffeine research
影响因子:
--
通讯作者:
Feinglos,MarkN
Feinglos,MarkN
中科院分区:
--
文献类型:
--
作者:
Lane,JamesD;Lane,AlexJ;Surwit,RichardS;Kuhn,CynthiaM;Feinglos,MarkN

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Background:A growing body of evidence suggests that caffeinated beverages may impair chronic glucose control in type 2 diabetes. This pilot study tested the chronic effects of caffeine abstinence on glucose control in type 2 diabetic patients who were daily coffee drinkers.Methods:Twelve coffee drinkers (six males) with established type 2 diabetes participated. Seven (five males) completed 3 months of total caffeine abstinence. Measures of chronic glucose control, long-term (hemoglobin A1c [HbA1c]) and short-term (1,5-anhydroglucitol [1,5-AG]), were collected at baseline and during follow-up. Abstinence was established by diaries confirmed by saliva caffeine assays.Results:Abstinence produced significant decreases in HbA1c and increases in 1,5-AG, both indicating improvements in chronic glucose control. Fasting glucose and insulin did not change, nor were changes in body weight observed.Conclusions:Although preliminary, these results suggest that caffeine abstinence may be beneficial for patients with type 2 diabetes. This hypothesis should be confirmed in larger controlled clinical trials.
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发表时间: 1989-04-01
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发表时间: 2007
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影响因子: --
作者:
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