Early-life exposure to home dampness associated with health effects among children in Chongqing, China
Early-life exposure to home dampness associated with health effects among children in Chongqing, China
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DOI：
10.1016/j.buildenv.2015.08.024
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发表时间：
2015-12
影响因子：
7.4
通讯作者：
Han Wang;Baizhan Li;Wei Yu;Juan Wang;D. Norbäck
中科院分区：
文献类型：
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作者：
Han Wang;Baizhan Li;Wei Yu;Juan Wang;D. Norbäck
本研究评估了 2917 名儿童（3-6 岁）的早期接触围产期潮湿问题与健康影响之间的关联。在逻辑回归模型中调整性别、年龄、哮喘或过敏家族史、环境烟草烟雾暴露、孕龄和房屋位置后，观察到围产期接触潮湿指标与过去12个月的一些呼吸道和过敏症状密切相关，包括喘息、夜间咳嗽、鼻炎和湿疹。在过去 12 个月中，仅在围产期接触大多数潮湿指标时，这些呼吸道和过敏症状的患病率显着增加，并且随着持续暴露（围产期加上当前暴露），这些症状的患病率进一步增加。仅当前暴露几乎没有如此显着的增加。这项研究发现，仅围产期暴露与医生诊断的疾病之间的关联较小，这些关联可能可以通过回忆偏差来解释。父母报告的早年接触围产期潮湿与中国重庆儿童目前的一些呼吸道和过敏症状显着相关。因此，有必要关注早期的生活环境，尤其是家庭潮湿，但其机制尚不清楚。
Associations between early-life exposure to perinatal dampness problems and health effects among 2917 children (3–6 years) were evaluated in this study. After adjusted for gender, age, family history of asthma or allergies, environmental tobacco smoke exposure, gestation age and house location in the logistic regression models, perinatal exposure to dampness indicators was observed to be strongly associated with some respiratory and allergic symptoms in the last 12 months, including wheezing, cough at night, rhinitis and eczema. The prevalence of theses respiratory and allergic symptoms in the last 12 months was significantly increased with perinatal-only exposure to most dampness indicators and was further increased with continuous exposure (perinatal plus current exposure). There was almost no such significant increase with current-only exposure. This study found less association between perinatal-only exposure and doctor-diagnosed diseases, and these associations may be explained by recall bias. Early-life exposure to perinatal dampness reported by parents was significantly associated with some current respiratory and allergic symptoms among children in Chongqing, China. Hence, it is necessary to pay attention to early living environment, especially home dampness, although the mechanisms are still unclear.