Prevalence and 10-Year Outcomes of Frailty in Older Adults in Relation to Deficit Accumulation

Prevalence and 10-Year Outcomes of Frailty in Older Adults in Relation to Deficit Accumulation
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DOI:
10.1111/j.1532-5415.2010.02764.x
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发表时间:
2010-04-01
影响因子:
6.3
通讯作者:
Rockwood, Kenneth
Rockwood, Kenneth
中科院分区:
医学1区
文献类型:
--
作者:
Song, Xiaowei;Mitnitski, Arnold;Rockwood, Kenneth

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目的评估老年人虚弱的患病率和10年预后与缺陷积累的关系。前瞻性队列研究。加拿大全国人口健康调查,以基线(1994/95年)估计的脆弱程度和2004/05年的死亡率跟踪情况。参与者:来自加拿大10个省的65至102岁的社区居住老年人(N= 2740, 60.8%为女性)。在10年的随访中,1208人死亡。测量方法使用自我报告的健康信息来构建虚弱指数(脆弱指数),作为个体累积缺陷的比例。主要结局指标是死亡率。结果男性和女性的衰弱患病率随着年龄的增长而增加(相关系数=0.955 ~ 0.994,P
OBJECTIVESTo evaluate the prevalence and 10-year outcomes of frailty in older adults in relation to deficit accumulation.DESIGNProspective cohort study.SETTINGThe National Population Health Survey of Canada, with frailty estimated at baseline (1994/95) and mortality follow-up to 2004/05.PARTICIPANTSCommunity-dwelling older adults (N=2,740, 60.8% women) aged 65 to 102 from 10 Canadian provinces. During the 10-year follow-up, 1,208 died.MEASUREMENTSSelf-reported health information was used to construct a frailty index (Frailty Index) as a proportion of deficits accumulated in individuals. The main outcome measure was mortality.RESULTSThe prevalence of frailty increased with age in men and women (correlation coefficient=0.955-0.994, P