First detection of the mcr-1 colistin resistance gene in Escherichia coli from a patient with urinary tract infection in Myanmar
First detection of the mcr-1 colistin resistance gene in Escherichia coli from a patient with urinary tract infection in Myanmar
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DOI：
10.1016/j.nmni.2019.100550
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发表时间：
2019-04
影响因子：
4
通讯作者：
N. San;M. S. Aung;P. Thu;Y. Myint;M. T. Aung;T. San;T. T. Mar-T.;M. Lwin;W. Maw;M. S. Hlaing;N. Kobayashi
中科院分区：
文献类型：
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作者：
N. San;M. S. Aung;P. Thu;Y. Myint;M. T. Aung;T. San;T. T. Mar-T.;M. Lwin;W. Maw;M. S. Hlaing;N. Kobayashi
2018年，在缅甸仰光一家三级医院收集的442株临床分离株中，在一份大肠杆菌样本中检测到了粘菌素耐药基因emcr-1。该菌株属于A-ST 23复合群，携带blaCTX-M-15和blaTEM-1，与喹诺酮类耐药决定区yrA和parC的多个突变有关。
Colistin-resistance genemcr-1was detected in anEscherichia colisample among 442 clinical isolates collected in a tertiary-care hospital in Yangon, Myanmar, in 2018. This isolate was classified into phylogroup A–ST23 complex and harbouredblaCTX-M-15andblaTEM-1, associated with multiple mutations in quinolone-resistance–determining regions ingyrAandparC.