Diagnosis of macular pseudoholes and lamellar macular holes by optical coherence tomography
Diagnosis of macular pseudoholes and lamellar macular holes by optical coherence tomography
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DOI：
10.1016/j.ajo.2004.06.088
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发表时间：
2004-11-01
影响因子：
4.2
通讯作者：
Gaudric, A
中科院分区：
文献类型：
--
作者：
Haouchine, B;Massin, P;Gaudric, A
目的：评价光学相干断层扫描(OCT)在黄斑假孔(MPH)和板层黄斑裂孔(LMH)鉴别诊断中的作用。设计：观察性病例系列。患者：我们回顾了连续70例患者的71只眼的文件，这些患者在OCT检查中被诊断为假孔或板层孔。所有在生物显微镜下怀疑为伪孔或板层孔的患者均行OCT检查。主要观察指标：每只眼接受6次以黄斑为中心的放射状3 mm OCT扫描，1次垂直扫描，1次6 mm水平扫描。视网膜厚度测量在中心凹中心，中心距中心750微米，垂直和水平。结果：40例黄斑病变患者，OCT均显示出MPH的黄斑轮廓特征：黄斑中心凹变陡，中心凹边缘增厚，中心凹直径较小。中心凹厚度正常或略有增加(167+/-42微米)。平均裂孔周围厚度大于正常(363+/-65微米)。在其他29例LMH患者中，OCT表现为黄斑中心凹底部变薄，中心凹边缘裂开，接近正常的中央凹周围视网膜厚度。中心凹厚度低于正常(72+/-19微米)。中心凹周围平均厚度接近正常(283+/-36)。光学相干断层扫描不能对其余两例病例进行分类。结论：光学相干断层扫描在区分由于视网膜前膜收缩引起的MPH和由于黄斑囊肿部分开放引起的LMH方面是非常有用的。(C)2004，由Elsevier Inc.保留所有权利。
PURPOSE: To assess the usefulness of optical coherence tomography (OCT) for better differential diagnosis of macular pseudoholes (MPH) and lamellar macular holes (LMH).DESIGN: Observational case series.METHODS: SETTING: Institutional practice. PATIENTS: We reviewed the files of 71 eyes of 70 consecutive patients who were diagnosed as having a pseudohole or lamellar hole on OCT examination. All patients referred for suspected pseudohole or lamellar hole on biomicroscopy were evaluated by OCT. MAIN OUTCOME MEASURES: Each eye underwent six radial 3-mm OCT scans centered on the macula, one 6-mm vertical and one 6-mm horizontal scan. Retinal thickness was measured at the foveal center and 750 mum from the center, vertically, and horizontally. The diameter of the macular contour was also measured on vertical and horizontal scans.RESULTS: In 40 cases, OCT showed a macular profile characteristic of MPH: a steepened foveal pit combined with thickened foveal edges and a small foveal pit diameter. Central foveal thickness was normal or slightly increased (167 +/- 42 mum). Mean perifoveal thickness was greater than normal (363 +/- 65 mum). In 29 other cases corresponding to LMH, OCT showed a profile characterized by a thin irregular foveal floor, split foveal edges, and near,normal perifoveal retinal thickness. Central foveolar thickness was thinner than normal (72 +/- 19 mum). Mean perifoveal thickness was near normal (283 +/- 36). Optical coherence tomography did not allow the classification of the remaining two cases.CONCLUSIONS: Optical coherence tomography is very useful in distinguishing MPH attributable to epiretinal membrane contraction from LMH because of partial opening of a macular cyst. (C) 2004 by Elsevier Inc. All rights reserved.