THE ACCURACY OF PATIENT REPORTS OF A FAMILY HISTORY OF CANCER
THE ACCURACY OF PATIENT REPORTS OF A FAMILY HISTORY OF CANCER
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DOI：
10.1016/0021-9681(85)90074-8
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发表时间：
1985-01-01
期刊：
影响因子：
--
通讯作者：
JOSTEN, DM
中科院分区：
文献类型：
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作者：
LOVE, RR;EVANS, AM;JOSTEN, DM
参考癌症遗传学诊所的121个连续的家系被研究。先证者提供了一级、二级和三级亲属发生癌症的详细书面历史，并在可能的情况下获得了验证每个报告的癌症病例的医疗记录。在180个一级亲属中的216例癌症患者中，83%的人正确地确定了原发癌症的部位。对于二级和三级亲属，原发癌症书面病史的准确率分别为67%和60%。应在流行病学研究中估计相应水平的错误的影响，并应激励临床医生在癌症家族史影响临床治疗的情况下寻找医疗记录。
One hundred and twenty-one consecutive families referred to a cancer genetics clinic were studied. The proband provided a detailed written history of cancers occurring in 1st, 2nd and 3rd degree relatives and medical records to validate each reported case of cancer were obtained where possible. For 216 cases of cancer in 180 first degree relatives, the primary cancer site was correctly identified in 83%. For 2nd and 3rd degree relatives the written histories of primary cancer were accurate for 67 and 60%, respectively. The effect of the corresponding levels of error should be estimated in epidemiologic studies and should motivate clinicians to seek medical records in situations where a family history of cancer influences clinical management.