Determination of kinetic rate and equilibrium binding constants for macromolecular interactions: a critique of the surface plasmon resonance literature.
Determination of kinetic rate and equilibrium binding constants for macromolecular interactions: a critique of the surface plasmon resonance literature.
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DOI：
10.1016/s0958-1669(05)80072-2
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发表时间：
1994-02-01
影响因子：
7.7
通讯作者：
O'Shannessy, D J
中科院分区：
文献类型：
--
作者：
O'Shannessy, D J
在过去的一年中，BIAcore系统（基于表面等离子体共振现象）在大分子相互作用的研究中越来越受欢迎。这种生物分子相互作用分析系统允许在实时和无标签模式下检测大分子相互作用。该技术的实时检测特性表明其在生成与生物分子相互作用动力学相关的数据方面的潜力。
Over the past year, the BIAcore system (which is based on the surface plasmon resonance phenomenon) has become increasingly popular for the study of macromolecular interactions. This biomolecular interaction analysis system allows the detection of macromolecular interactions in real time and in a label-free mode. The real-time detection properties of this technique suggest its potential in the generation of data relating to the kinetics of interaction of biomolecules.