An omission procedure reorganizes the microstructure of sign-tracking while preserving incentive salience
An omission procedure reorganizes the microstructure of sign-tracking while preserving incentive salience
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DOI：
10.1101/lm.041574.115
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发表时间：
2016-04-01
影响因子：
2
通讯作者：
Smith, Kyle S.
中科院分区：
文献类型：
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作者：
Chang, Stephen E.;Smith, Kyle S.
欲望符号追踪，其中奖励配对线索引起的方法，可以导致线索的相互作用，演示了如何线索获得动机价值。例如，大鼠将接近并随后与杠杆插入提示相互作用，该杠杆插入提示在其缩回时发出食物递送信号。然而，杠杆偏转迅速减少，一旦大鼠接受训练的遗漏时间表，杠杆相互作用取消食物输送。在这里，我们评估的变化，标志跟踪反应地形暴露于这样的遗漏程序。当他们取消奖励时，杠杆偏转急剧下降。然而，在遗漏时间表上的大鼠继续接近、嗅闻和接触杠杆而不按压它，并且与不在遗漏时间表下的大鼠以相当的速率这样做。因此，在省略之后，仍然保留了标记追踪，尽管方式有所不同。这些发现表明，奖励线索的动机吸引力可以表现出显着的持久性和灵活性。
Appetitive sign-tracking, in which reward-paired cues elicit approach that can result in cue interaction, demonstrates how cues acquire motivational value. For example, rats will approach and subsequently interact with a lever insertion cue that signals food delivery upon its retraction. However, lever deflections are rapidly reduced once rats are trained on an omission schedule in which lever interactions cancel food delivery. Here we evaluated the change in sign-tracking response topography in rats exposed to such an omission procedure. Lever deflections dropped precipitously when they canceled reward. However, rats that were on an omission schedule continued to approach, sniff, and contact the lever without pressing it, and did so at comparable rates to rats that were not under an omission schedule. Thus, sign-tracking was maintained, albeit in a different manner, following omission. Such findings show that the motivational attraction to reward cues can be expressed with remarkable persistence and flexibility.