Localized illumination of the Aplysia and Bulla eye reveals new relationships between retinal layers.
Localized illumination of the Aplysia and Bulla eye reveals new relationships between retinal layers.
复制标题
海兔和大泡眼的局部照明揭示了视网膜层之间的新关系。
DOI：
10.1016/0006-8993(83)91343-4
复制
发表时间：
1983
期刊：
影响因子：
2.9
通讯作者：
McMahon,DG
中科院分区：
文献类型：
--
作者：
Block,GD;McMahon,DG
后鳃视网膜的细胞组织令人感兴趣，因为其中几种软体动物的眼睛以视神经脉冲频率表达昼夜节律。在 Audersirk 提出的视网膜组织模型中，光感受器与高级细胞产生电接触，从而产生视神经中记录的复合动作电位 (CAP)。然而，通过对选定的视网膜区域使用微照明，我们现在发现视网膜基底附近的细胞负责导致 CAP 的光传导。晶状体周围感光器远端部分的照明会在没有 CAP 的视神经中产生低幅度的单一活动。此外，该区域的照明会导致自发 CAP 或由视网膜基底照明产生的 CAP 的抑制。这种抑制被高镁-低钙溶液阻断，因此我们得出结论，抑制和分泌步骤至少构成光感受器层和产生 CAP 的神经元之间的路径的一部分。
The cellular organization of the opisthobranch retina is of interest since the eyes of several of these molluscs express circadian rhythms in optic nerve impulse frequency. In a model for retinal organization proposed by Audersirk, photoreceptors make electrical contancts with higher order cells which generate the compound action potential (CAP) recorded in the optic nerve. However, using micro-illumination on selected retinal regions, we now find that cells near the base of the retina are responsible for light transduction leading to CAPs. Illumination of the distal segments of photoreceptors surrounding the lens generates low-amplitude unitary activity in the optic nerve without CAPs. Furthermore, illumination of this region leads to inhibition of spontaneous CAPs or those generated by illumination of the retinal base. This inhibition is blocked by high magnesium-low calcium solutions and thus we conclude that inhibition and a secretory step comprise at least part of the pathway between the photoreceptor layer and neurons giving rise to the CAP.