Effect of harmless acute pancreatitis score, red cell distribution width and neutrophil/lymphocyte ratio on the mortality of patients with nontraumatic acute pancreatitis at the emergency department
Effect of harmless acute pancreatitis score, red cell distribution width and neutrophil/lymphocyte ratio on the mortality of patients with nontraumatic acute pancreatitis at the emergency department
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DOI：
10.5847/wjem.j.1920-8642.2015.01.005
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发表时间：
2015-01-01
影响因子：
2.1
通讯作者：
Sogut, Ozgur
中科院分区：
文献类型：
--
作者：
Gulen, Bedia;Sonmez, Ertan;Sogut, Ozgur
背景技术背景：采用无创性急性胰腺炎评分（HAPS）、中性粒细胞/淋巴细胞比值和红细胞分布宽度（RDW）对急诊科诊断为非创伤性急性胰腺炎患者的早期预后进行评估。慢性胰腺炎患者和档案中缺失数据的患者被排除在研究之外。没有在艾德进行计算机断层扫描（CT）的患者不包括在研究中。患者的中位年龄为53.1岁（IQR=36-64）。在这些患者中，68.1%（n=226）有胆道病因。这些患者在最初48小时内的死亡率为4.3%（n=14）。在使用Balthazar分类、HAPS评分、RDW、中性粒细胞/淋巴细胞比率、年龄、糖尿病和收缩压进行的Logistic回归分析中，确定死亡率的唯一自变量被指定为Balthazar分类（OR：15; 95% CI：3.5至64.4）。HAPS、中性粒细胞/淋巴细胞比率和RDW不能有效地确定非创伤性急性胰腺炎病例最初48小时内的死亡率。决定死亡率的唯一自变量是Balthazar分级。
BACKGROUND: Harmless acute pancreatitis score (HAPS), neutrophile/lymphocyte ratio and red blood cell distribution width (RDW) are used to determine the early prognosis of patients diagnosed with nontraumatic acute pancreatitis in the emergency department (ED).METHODS: Patients diagnosed with acute pancreatitis (K 85.9) in the ED according to the ICD10 coding during one year were included in the study. Patients with chronic pancreatitis and those who had missing data in their files were excluded from the study. Patients who did not have computed tomography (CT) in the ED were not included in the study.RESULTS: Ultimately, 322 patients were included in the study. The median age of the patients was 53.1 (IQR=36-64). Of the patients, 68.1% (n=226) had etiological causes of the biliary tract. The mortality rate of these patients within the first 48 hours was 4.3% (n=14). In the logistic regression analysis performed by using Balthazar classification, HAPS score, RDW, neutrophile/lymphocyte ratio, age, diabetes mellitus and systolic blood pressure, the only independent variable in determining mortality was assigned as Balthazar classification (OR: 15; 95% CI : 3.5 to 64.4).CONCLUSIONS: HAPS, neutrophile/lymphocyte ratio and RDW were not effective in determining the mortality of nontraumatic acute pancreatitis cases within the first 48 hours. The only independent variable for determining the mortality was Balthazar classification.