An Update on the Impact of Postnatal Systemic Corticosteroids on Mortality and Cerebral Palsy in Preterm Infants: Effect Modification by Risk of Bronchopulmonary Dysplasia
An Update on the Impact of Postnatal Systemic Corticosteroids on Mortality and Cerebral Palsy in Preterm Infants: Effect Modification by Risk of Bronchopulmonary Dysplasia
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DOI：
10.1016/j.jpeds.2014.07.049
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发表时间：
2014-12-01
影响因子：
5.1
通讯作者：
Sinclair, John C.
中科院分区：
文献类型：
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作者：
Doyle, Lex W.;Halliday, Henry L.;Sinclair, John C.
根据先前对 14 项随机对照试验数据的元回归，患有支气管肺发育不良风险较高的婴儿在产后皮质类固醇治疗后，无脑瘫的生存率有所提高。根据 20 项随机对照试验的数据进行的更新分析，这种关系依然存在，而且更加牢固。
Infants at higher risk of bronchopulmonary dysplasia had increased rates of survival free of cerebral palsy after postnatal corticosteroid treatment in a previous metaregression of data from 14 randomized controlled trials. The relationship persists and is stronger in an updated analysis with data from 20 randomized controlled trials.