Plasma B-Type Natriuretic Peptide Level and Cardiovascular Events in Chronic Kidney Disease in a Community-Based Population
Plasma B-Type Natriuretic Peptide Level and Cardiovascular Events in Chronic Kidney Disease in a Community-Based Population
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DOI：
10.1253/circj.cj-09-0834
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发表时间：
2010-04-01
影响因子：
3.3
通讯作者：
Okayama, Akira
中科院分区：
文献类型：
--
作者：
Sakuma, Masafumi;Nakamura, Motoyuki;Okayama, Akira
背景资料：血浆B型利钠肽（BNP）水平混淆肾功能不全，因此，本研究探讨血浆BNP是否可能是一个可靠的生物标志物的心血管（CV）事件的发病在一个以人口为基础的队列肾功能受损。方法和结果：基线数据，包括血浆BNP，血清肌酐和尿蛋白水平，确定在参与者从社区为基础的人口。计算估计肾小球滤过率（eGFR），慢性肾脏疾病（CKD）定义为：eGFR
Background: Plasma B-type natriuretic peptide (BNP) levels are confounded by renal dysfunction, so this study examined whether plasma BNP might be a reliable biomarker of the onset of cardiovascular (CV) events in a population-based cohort with impaired renal function.Methods and Results: Baseline data, including plasma BNP, serum creatinine, and urinary protein levels, were determined in participants from a community-based population. Estimated glomerular filtration rate (eGFR) was calculated, and chronic kidney disease (CKD) was defined as either: eGFR