A long-term evaluation of very low calorie semi-synthetic diets: an inpatient/outpatient study with egg albumin as the protein source.
A long-term evaluation of very low calorie semi-synthetic diets: an inpatient/outpatient study with egg albumin as the protein source.
复制标题
极低热量半合成饮食的长期评估：以卵白蛋白作为蛋白质来源的住院/门诊研究。
DOI：
--
复制
发表时间：
1977
影响因子：
4.9
通讯作者：
Baird Im
中科院分区：
文献类型：
--
作者：
H. An;Baird Im
： 52例肥胖患者作为住院患者进行了为期两周的初步研究，他们采用极低热量饮食，含0.76-1.34 MJ (180-320 kcal)， 15-40 g蛋白蛋白，30-40 g低聚糖，维生素和矿物质。病人出院后每周见一次。41名患者能够继续治疗超过8周，29名患者能够持续治疗超过16周。体重减轻方面，体重减轻至少10kg的有41例，体重减轻至少15kg的有29例，体重减轻至少20kg的有14例；17名患者的体重低于理想体重15公斤。在碳水化合物40克/天的情况下，达到氮平衡所需的鸡蛋白蛋白量估计约为25克/天。所有患者出院后均能恢复正常活动，治疗无重大副作用。临床常规、生化及血液学检查未见明显变化。特别是血清蛋白、电解质、尿酸、胆固醇、血红蛋白和红细胞压积未受影响。酮症极少或不存在。结论：极低热量半合成饮食是肥胖患者减肥的一种可行、安全的方法。
: Fifty-two obese patients were studied initially for two weeks as inpatients on very low calorie diets, containing 0.76-1.34 MJ (180-320 kcal) as 15-40 g egg albumin, 30-40 g oligosaccharides, vitamins and minerals. Patients were seen weekly after discharge from hospital. Forty-one patients were able to continue treatment for more than eight weeks, and 29 for more than 16 weeks. In terms of weight loss, 41 patients lost at least 10 kg body weight, 29 at least 15 kg, and 14 at least 20 kg; 17 patients came within 15 kg of their ideal body weight. With 40 g/day carbohydrate, the quantity of egg albumin required to give nitrogen equilibrium was estimated to be about 25 g/day. All patients were able to resume their normal activities on discharge from hospital and had no major side-effects from treatment. Routine clinical, biochemical and haematological examinations showed no significant changes. In particular, serum proteins, electrolytes, uric acid, cholesterol and blood haemoglobin and haematocrit were unaffected. Ketosis was minimal or absent. It is concluded that the use of very low calorie semi-synthetic diets is a feasible and safe method of weight reduction for obese patients.