Tungsten Toxicity in Plants.
Tungsten Toxicity in Plants.
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DOI：
10.3390/plants1020082
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发表时间：
2012-11-16
期刊：
影响因子：
--
通讯作者：
Eleftheriou EP
中科院分区：
文献类型：
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作者：
Adamakis ID;Panteris E;Eleftheriou EP
钨（W）是一种稀有的重金属，由于其独特的物理性质，广泛应用于工业、军事和家用领域。这些活动不可避免地导致了当地高浓度的W积累，引起了人们对其对生物体影响的担忧。在植物中，W主要被用作抗氧化酶的抑制剂，因为它拮抗钼（Mo）对这些酶的钼辅因子（MoCo）。然而，最近的进展表明，除了钼酶抑制，W具有与其他重金属类似的毒性属性。这些影响包括幼苗生长受阻、根和地上部生物量减少、细胞组分的超微结构畸形、细胞周期畸变、细胞骨架破坏以及与程序性细胞死亡（PCD）相关的基因表达失调。本文综述了近年来有关钨对植物和植物细胞毒性的研究进展，并指出了存在的知识缺口和最有意义的研究方向。
Tungsten (W) is a rare heavy metal, widely used in a range of industrial, military and household applications due to its unique physical properties. These activities inevitably have accounted for local W accumulation at high concentrations, raising concerns about its effects for living organisms. In plants, W has primarily been used as an inhibitor of the molybdoenzymes, since it antagonizes molybdenum (Mo) for the Mo-cofactor (MoCo) of these enzymes. However, recent advances indicate that, beyond Mo-enzyme inhibition, W has toxic attributes similar with those of other heavy metals. These include hindering of seedling growth, reduction of root and shoot biomass, ultrastructural malformations of cell components, aberration of cell cycle, disruption of the cytoskeleton and deregulation of gene expression related with programmed cell death (PCD). In this article, the recent available information on W toxicity in plants and plant cells is reviewed, and the knowledge gaps and the most pertinent research directions are outlined.